Multiple vertebral fractures may occur following discontinuation of treatment with Prolia, particularly in patients with a history of vertebral fracture.1
Advise patients not to interrupt Prolia therapy without their physician’s advice.1
Evaluate the individual benefit/risk before discontinuing treatment with Prolia.1
If Prolia treatment is discontinued, consider transitioning to an alternative antiresorptive therapy.1
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|Prolia Product Monograph. Amgen Canada Inc., December 21, 2022.